© 2026. The Author(s). Published by the American Astronomical Society.Zhang, LuluPackham, ChristopherHicks, Erin K. S.García Bernete, IsmaelAlonso-Herrero, AlmudenaDavies, R. I.Ward, Martin J.Delaney, DanielIzumi, TakumaRigopoulou, DimitraRamos Almeida, CristinaGonzález Martín, OmairaRiffel, Rogemar A.Ricci, ClaudioVillar Martín, MontserratCombes, FrancoisePereira Santaella, MiguelHönig, SebastianBunker, AndrewBoorman, PeterBellocchi, EnricaLevenson, Nancy A.García-Burillo, SantiagoDonnan, FergusAudibert, AneliseFuller, LindsayDíaz Santos, TanioRosario, David J.2026-09-182026-09-182026-08-20The Astrophysical Journal Letters 1007(2): L5220418205https://iopscience.iop.org/article/10.3847/2041-8213/ae96b6https://hdl.handle.net/20.500.12666/1902This Letter presents JWST MIRI/Medium-Resolution Spectrometer (MRS) observations of the central r ≈ 40–240 pc regions of five active galactic nuclei (AGN) spanning a wide range of luminosities (log Lbol/erg s−1 ≈ 39.8–43.8). Combining multiphase diagnostics from polycyclic aromatic hydrocarbons (PAHs), molecular hydrogen (H2), and ionized gas at spatial scales of ∼4–24 pc, this study presents a spatially resolved investigation into the effects of the two distinct AGN feedback modes—radiative and kinetic—on the surrounding medium. The results indicate that these two feedback modes, associated with AGN irradiation and shock processing, respectively, collectively drive the relative suppression of PAH emission in the nuclear regions of the targets studied here. Moreover, the coexistence of these two AGN feedback modes, especially the shock processing associated with either jets or outflows, in the central regions of AGN naturally explains both the bimodal distribution of PAH band ratios observed in the targets studied here and the seemingly disparate results reported in the literature. Although based on a limited sample, these findings provide new insights into calibrating star formation rates from PAH emission in AGN and, more importantly, lay the groundwork for a practical framework to diagnose and quantify AGN feedback in the JWST era.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Active galactic nucleiInfrared spectroscopyInterstellar dust processesInterstellar line emissionJames Webb Space TelescopeMolecular gasPolycyclic aromatic hydrocarbonsShocksinfo:eu-repo/semantics/article10.3847/2041-8213/ae96b6http://dx.doi.org/10.13039/501100004263http://dx.doi.org/10.13039/501100003593http://dx.doi.org/10.13039/501100002322http://dx.doi.org/10.13039/501100011033http://dx.doi.org/10.13039/100000104https://doi.org/10.13039/100013757http://dx.doi.org/10.13039/100012818http://dx.doi.org/10.13039/501100000780http://dx.doi.org/10.13039/501100005739info:eu-repo/semantics/openAccess