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Campo DC | Valor | Idioma |
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dc.contributor.author | García López, Eva | - |
dc.contributor.author | Alcazar, P. | - |
dc.contributor.author | Cid, Cristina | - |
dc.contributor.other | Unidad de Excelencia Científica María de Maeztu del Centro de Astrobiología del Instituto Nacional de Técnica Aeroespacial y CSIC, MDM-2017-0737 | - |
dc.date.accessioned | 2022-02-11T11:19:22Z | - |
dc.date.available | 2022-02-11T11:19:22Z | - |
dc.date.issued | 2021-08-04 | - |
dc.identifier.citation | Biomolecules 11(8): 1155(2021) | es |
dc.identifier.other | https://www.mdpi.com/2218-273X/11/8/1155 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.12666/523 | - |
dc.description | Academic Editor: Michael Van Dyke | es |
dc.description.abstract | Cold-loving microorganisms of all three domains of life have unique and special abilities that allow them to live in harsh environments. They have acquired structural and molecular mechanisms of adaptation to the cold that include the production of anti-freeze proteins, carbohydrate-based extracellular polymeric substances and lipids which serve as cryo- and osmoprotectants by maintaining the fluidity of their membranes. They also produce a wide diversity of pigmented molecules to obtain energy, carry out photosynthesis, increase their resistance to stress and provide them with ultraviolet light protection. Recently developed analytical techniques have been applied as high-throughoutput technologies for function discovery and for reconstructing functional networks in psychrophiles. Among them, omics deserve special mention, such as genomics, transcriptomics, proteomics, glycomics, lipidomics and metabolomics. These techniques have allowed the identification of microorganisms and the study of their biogeochemical activities. They have also made it possible to infer their metabolic capacities and identify the biomolecules that are parts of their structures or that they secrete into the environment, which can be useful in various fields of biotechnology. This Review summarizes current knowledge on psychrophiles as sources of biomolecules and the metabolic pathways for their production. New strategies and next-generation approaches are needed to increase the chances of discovering new biomolecules. | es |
dc.description.sponsorship | This research was funded by the Spanish State Research Agency (AEI), Projects PID2019- 104205GB-C22 and MDM-2017-0737, Centro de Astrobiología (CSIC-INTA), Unidad de Excelencia María de Maeztu. Eva Garcia-Lopez is supported by a fellowship (PTA2016-12325-I) provided by the Spanish Ministry of Science and Innovation. | es |
dc.language.iso | eng | es |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | es |
dc.relation | info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-104205GB-C22 | - |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | es |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | Biomolecules | es |
dc.subject | Microorganisms | es |
dc.subject | Proteins | es |
dc.subject | Metabolites | es |
dc.subject | Pigments | es |
dc.subject | Antibiotics | es |
dc.subject | Antifreeze molecules | es |
dc.subject | Lipids | es |
dc.subject | Omics | es |
dc.subject | Metabolic routes | es |
dc.title | Identification of Biomolecules Involved in the Adaptation to the Environment of Cold-Loving Microorganisms and Metabolic Pathways for Their Production | es |
dc.type | info:eu-repo/semantics/article | es |
dc.contributor.orcid | Alcazar, P. [0000-0002-2276-5376] | - |
dc.contributor.orcid | Cid, C. [0000-0001-5128-4558] | - |
dc.identifier.doi | 10.3390/biom11081155 | - |
dc.identifier.e-issn | 2218-273X | - |
dc.contributor.funder | Agencia Estatal de Investigación (AEI) | - |
dc.description.peerreviewed | Peerreview | es |
dc.identifier.funder | http://dx.doi.org/10.13039/501100011033 | - |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | - |
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