Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12666/1044
| Title: | Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: implications for the pathogenesis of free radical-induced neurodegenerative disorders |
| Authors: | Peraile, I. Granado, Noelia Torres, Elisa Gutiérrez López, María Dolores Moratalla, Rosario Colado, Isabel O’Shea, Esther |
| Keywords: | Oxidative stress;3,4-Methylenedioxymethamphetamine;Dopamine neurotoxicity;Cocaine |
| Issue Date: | 17-May-2013 |
| Publisher: | Springer Nature |
| DOI: | 0.1007/s00213-013-3142-5 |
| Published version: | https://link.springer.com/article/10.1007/s00213-013-3142-5 |
| Citation: | Psychopharmacology (2013) 230:125–135 |
| Abstract: | The drugs of abuse 3,4-methylenedioxymethamphetamine (MDMA; “ecstasy”) and cocaine both increase the generation of free radicals, and in the case of MDMA, this increase in oxidative stress is involved in the dopaminergic neurotoxicity produced by the drug in mice. Oxidative stress processes are also involved in the pathogenesis of several neurodegenerative diseases. |
| URI: | http://hdl.handle.net/20.500.12666/1044 |
| Appears in Collections: | (Terrestre) Artículos |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Peraile2013_Cocaine potentiates MDMA-induced oxidative stress.pdf | 334,26 kB | Adobe PDF |  View/Open |
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